rs10859172 - LINC02823 - LINC03130

Magnitude 2.2 · 1 study on file

Reported associations

• Genetic association analysis of human median voice pitch identifies a common locus for tonal and non-tonal languages - Unknown journal (n.d.) · Unknown authors · PubMed 38714798

  ABSTRACT: The genetic influence on human vocal pitch in tonal and non-tonal languages remains largely unknown. In tonal languages, such as Mandarin Chinese, pitch changes differentiate word meanings, whereas in non-tonal languages, such as Icelandic, pitch is used to convey intonation. We addressed this question by searching for genetic associations with interindividual variation in median pitch in a Chinese major depression case-control cohort and compared our results with a genome-wide association study from Iceland. The same genetic variant, rs11046212-T in an intron of the ABCC9 gene, was one of the most strongly associated loci with median pitch in both samples. Our meta-analysis revealed four genome-wide significant hits, including two novel associations. The discovery of genetic var

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