rs10844026 - RNU6-1069P - LINC02422

Magnitude 2.2 · 1 study on file

Reported associations

• A Preliminary Genome-Wide Association Study of Pain-Related Fear: Implications for Orofacial Pain - Unknown journal (n.d.) · Unknown authors · PubMed 28701861

  ABSTRACT: Background Acute and chronic orofacial pain can significantly impact overall health and functioning. Associations between fear of pain and the experience of orofacial pain are well-documented, and environmental, behavioral, and cognitive components of fear of pain have been elucidated. Little is known, however, regarding the specific genes contributing to fear of pain. Methods A genome-wide association study (GWAS; N = 990) was performed to identify plausible genes that may predispose individuals to various levels of fear of pain. The total score and three subscales (fear of minor, severe, and medical/dental pain) of the Fear of Pain Questionnaire-9 (FPQ-9) were modeled in a variance components modeling framework to test for genetic association with 8.5 M genetic variants acros

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