rs10831734 - MICAL2

Magnitude 2.8 · 1 study on file

Reported associations

• Genome‐wide analyses of aggressiveness in attention‐deficit hyperactivity disorder Genome‐Wide Analyses of Aggressiveness in Attention‐Deficit Hyperactivity Disorder - Unknown journal (n.d.) · Unknown authors · PubMed 27021288

  ABSTRACT: Aggressiveness is a behavioral trait that has the potential to be harmful to individuals and society. With an estimated heritability of about 40%, genetics is important in its development. We performed an exploratory genome‐wide association (GWA) analysis of childhood aggressiveness in attention deficit hyperactivity disorder (ADHD) to gain insight into the underlying biological processes associated with this trait. Our primary sample consisted of 1,060 adult ADHD patients (aADHD). To further explore the genetic architecture of childhood aggressiveness, we performed enrichment analyses of suggestive genome‐wide associations observed in aADHD among GWA signals of dimensions of oppositionality (defiant/vindictive and irritable dimensions) in childhood ADHD (cADHD). No single po

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