rs10827614 - LINC02630 - MTND5P17

Magnitude 4.5 · 1 study on file

Reported associations

• The link between liver fat and cardiometabolic diseases is highlighted by genome-wide association study of MRI-derived measures of body composition - Unknown journal (n.d.) · Unknown authors · PubMed 36402844

  ABSTRACT: Obesity and associated morbidities, metabolic associated fatty liver disease (MAFLD) included, constitute some of the largest public health threats worldwide. Body composition and related risk factors are known to be heritable and identification of their genetic determinants may aid in the development of better prevention and treatment strategies. Recently, large-scale whole-body MRI data has become available, providing more specific measures of body composition than anthropometrics such as body mass index. Here, we aimed to elucidate the genetic architecture of body composition, by conducting genome-wide association studies (GWAS) of these MRI-derived measures. We ran both univariate and multivariate GWAS on fourteen MRI-derived measurements of adipose and muscle tissue distribu

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