rs10827317 - LINC02629 - PARD3
Magnitude 4.5 · 1 study on file
Reported associations
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Genome‐Wide Association Study of Liver Fat: The Multiethnic Cohort Adiposity Phenotype Study - Unknown journal (n.d.) · Unknown authors · PubMed 32766472
ABSTRACT: The global rise in fatty liver is a major public health problem. Thus, it is critical to identify both global and population‐specific genetic variants associated with liver fat. We conducted a genome‐wide association study (GWAS) of percent liver fat and nonalcoholic fatty liver disease (NAFLD) assessed by magnetic resonance imaging in 1,709 participants from the population‐based Multiethnic Cohort Adiposity Phenotype Study. Our participants comprised older adults of five U.S. racial/ethnic groups: African Americans (n = 277), Japanese Americans (n = 424), Latinos (n = 348), Native Hawaiians (n = 274), and European Americans (n = 386). The established missense risk variant rs738409 located in patatin‐like phospholipase domain containing 3 (PNPLA3) at 22q13 was c
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