rs10825036 - RNA5SP318 - PCDH15

Magnitude 4.5 · 1 study on file

Reported associations

• Prediction of Breast Cancer Survival Using Clinical and Genetic Markers by Tumor Subtypes - Unknown journal (n.d.) · Unknown authors · PubMed 25867717

  ABSTRACT: Purpose To identify the genetic variants associated with breast cancer survival, a genome-wide association study (GWAS) was conducted of Korean breast cancer patients. Methods From the Seoul Breast Cancer Study (SEBCS), 3,226 patients with breast cancer (1,732 in the discovery and 1,494 in the replication set) were included in a two-stage GWAS on disease-free survival (DFS) by tumor subtypes based on hormone receptor (HR) and human epidermal growth factor receptor 2 (HER2). The associations of the re-classified combined prognostic markers through recursive partitioning analysis (RPA) of DFS for breast cancer were assessed with the Cox proportional hazard model. The prognostic predictive values of the clinical and genetic models were evaluated by Harrell's C. Results In the two-

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