rs10815381 - IL33

Magnitude 2.8 · 1 study on file

Reported associations

• A Genome-Wide Association Study to Identify Single-Nucleotide Polymorphisms for Acute Kidney Injury. - American journal of respiratory and critical care medicine (2017) · Zhao B, Lu Q, Cheng Y, Belcher JM, Siew ED, Leaf DE, Body SC, Fox AA, Waikar SS, Collard CD, Thiessen-Philbrook H, Ikizler TA, Ware LB, Edelstein CL, Garg AX, Choi M, Schaub JA, Zhao H, Lifton RP, Parikh CR · PubMed 27576016

  Acute kidney injury is a common and severe complication of critical illness and cardiac surgery. Despite significant attempts at developing treatments, therapeutic advances to attenuate acute kidney injury and expedite recovery have largely failed. Identifying genetic loci associated with increased risk of acute kidney injury may reveal novel pathways for therapeutic development. We conducted an exploratory genome-wide association study to identify single-nucleotide polymorphisms associated with genetic susceptibility to in-hospital acute kidney injury. We genotyped 609,508 single-nucleotide polymorphisms and performed genotype imputation in 760 acute kidney injury cases and 669 controls. We then evaluated polymorphisms that showed the strongest association with acute kidney injury in a re

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