rs10813374 - RPS26P2 - FTLP4

Magnitude 2.0 · 1 study on file

Reported associations

• Genome-wide SNP Associations with Rubella-Specific Cytokine Responses in Measles-Mumps-Rubella Vaccine Recipients - Unknown journal (n.d.) · Unknown authors · PubMed 24811271

  ABSTRACT: Genetic polymorphisms are known to affect responses to both viral infection and vaccination. Our previous work has described genetic polymorphisms significantly associated with variations in immune response to rubella vaccine from multiple gene families with known immune function, including: HLA, cytokine and cytokine receptor genes, and in genes controlling innate and adaptive immunity. In this study, we assessed cellular immune responses (IFNγ and IL-6) in a cohort of healthy younger individuals and performed genome wide SNP analysis on these same individuals. Here, we report the first genome-wide association study focused on immune responses following rubella vaccination. Our results indicate that rs16928280 in PTPRD (protein tyrosine phosphatase delta) and a collection of SN

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