rs10802346 - SMYD3

Magnitude 2.2 · 1 study on file

Reported associations

• Fractional exhaled nitric oxide in childhood is associated with 17q11.2-q12 and 17q12-q21 variants - Unknown journal (n.d.) · Unknown authors · PubMed 24315451

  ABSTRACT: Background The fractional concentration of nitric oxide in exhaled air (FeNO) is a biomarker of eosinophilic airway inflammation and associated with childhood asthma. Identification of common genetic variants associated with childhood FeNO may help to define biological mechanisms related to specific asthma phenotypes. Objective To identify genetic variants associated with childhood FeNO, and their relation with asthma. Methods FeNO was measured in children aged 5 to 15 years. In 14 genome-wide association (GWA) studies (N = 8,858), we examined the associations of ~2.5 million single nucleotide polymorphisms (SNPs) with FeNO. Subsequently, we assessed whether significant SNPs were expression quantitative trait loci (eQTLs) in genome-wide expression datasets of lymphoblastoid cell

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