rs10800682 - CCNQP1 - LINC00862

Magnitude 2.0 · 1 study on file

Reported associations

• Genetic meta-analysis of twin birth weight shows high genetic correlation with singleton birth weight - Unknown journal (n.d.) · Unknown authors · PubMed 33955455

  ABSTRACT: Abstract Birth weight (BW) is an important predictor of newborn survival and health and has associations with many adult health outcomes, including cardiometabolic disorders, autoimmune diseases and mental health. On average, twins have a lower BW than singletons as a result of a different pattern of fetal growth and shorter gestational duration. Therefore, investigations into the genetics of BW often exclude data from twins, leading to a reduction in sample size and remaining ambiguities concerning the genetic contribution to BW in twins. In this study, we carried out a genome-wide association meta-analysis of BW in 42 212 twin individuals and found a positive correlation of beta values (Pearson's r = 0.66, 95% confidence interval [CI]: 0.47-0.77) with 150 previously r

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