rs10789446 - LINC01685 - HSPA5P1

Magnitude 4.5 · 1 study on file

Reported associations

• Nightmares share genetic risk factors with sleep and psychiatric traits. - Translational psychiatry (2024) · Ollila HM, Sinnott-Armstrong N, Kantojärvi K, Broberg M, Palviainen T, Jones S, Ripatti V, Pandit A, Rong R, Kristiansson K, Sandman N, Valli K, Hublin C, Ripatti S, Widen E, Kaprio J, Saxena R, Paunio T · PubMed 38413574

  Nightmares are vivid, extended, and emotionally negative or negative dreams that awaken the dreamer. While sporadic nightmares and bad dreams are common and generally harmless, frequent nightmares often reflect underlying pathologies of emotional regulation. Indeed, insomnia, depression, anxiety, or alcohol use have been associated with nightmares in epidemiological and clinical studies. However, the connection between nightmares and their comorbidities are poorly understood. Our goal was to examine the genetic risk factors for nightmares and estimate correlation or causality between nightmares and comorbidities. We performed a genome-wide association study (GWAS) in 45,255 individuals using a questionnaire-based assessment on the frequency of nightmares during the past month and genome-wi

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