rs10788473 - GRID1

Magnitude 2.8 · 1 study on file

Reported associations

• Genome-Wide Association Study of Survival in Patients with Pancreatic Adenocarcinoma - Unknown journal (n.d.) · Unknown authors · PubMed 23180869

  ABSTRACT: Objective Survival of patients with pancreatic adenocarcinoma is limited and few prognostic factors are known. We conducted a two-stage genome-wide association study (GWAS) to identify germline variants associated with survival in patients with pancreatic adenocarcinoma. Design We analyzed overall survival in relation to single nucleotide polymorphisms (SNPs) among 1,005 patients from two large GWAS datasets, PanScan I and ChinaPC. Cox proportional hazards regression was used in an additive genetic model with adjustment for age, sex, clinical stage and the top four principal components of population stratification. The first stage included 642 cases of European ancestry (PanScan), from which the top SNPs (P≤10−5) were advanced to a joint analysis with 363 additional patients

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