rs10786764 - NRG3

Magnitude 2.0 · 1 study on file

Reported associations

• Genome-wide association study for the interaction between BMR and BMI in obese Korean women including overweight - Nutrition research and practice (2016) · Lee M, Kwon DY, Kim MS, Choi CR, Park MY, Kim AJ · PubMed 26865924

  ABSTRACT: BACKGROUND/OBJECTIVES This is the first study to identify common genetic factors associated with the basal metabolic rate (BMR) and body mass index (BMI) in obese Korean women including overweight. This will be a basic study for future research of obese gene-BMR interaction. SUBJECTS/METHODS The experimental design was 2 by 2 with variables of BMR and BMI. A genome-wide association study (GWAS) of single nucleotide polymorphisms (SNPs) was conducted in the overweight and obesity (BMI > 23 kg/m2) compared to the normality, and in women with low BMR (< 1426.3 kcal/day) compared to high BMR. A total of 140 SNPs reached formal genome-wide statistical significance in this study (P < 1 × 10-4). Surveys to estimate energy intake using 24-h recall method for three days and questionnaire

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