rs10783124 - AGL - SLC35A3

Magnitude 4.5 · 1 study on file

Reported associations

• Genetic risk score raises the risk of incidence of chronic kidney disease in Korean general population-based cohort. - Clinical and experimental nephrology (2020) · Yun S, Han M, Kim HJ, Kim H, Kang E, Kim S, Ahn C, Oh KH · PubMed 30955190

  Chronic kidney disease (CKD) is a common disease, affecting about 10% of the general population. The genetic component about CKD incidence in Asian population is not well known. The aim of the study is to find the genetic loci associated with incident CKD and to figure out the effect of genetic variation on the development of CKD. We conducted a genome-wide association (GWA) study regarding the development of CKD based on two population-based cohorts of Korean Genome Epidemiology Study. 3617 Koreans from two different cohorts, aged 40-49 years without CKD at initial visit, were included in our analysis. We used 2510 individuals in Ansan as the discovery set and another 1107 individuals from Ansung as the replication set. At baseline, members of both cohorts provided information on creatin

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