rs10778569 - PWP1

Magnitude 2.2 · 1 study on file

Reported associations

• Genome-wide association study of psychiatric and substance use comorbidity in Mexican individuals - Unknown journal (n.d.) · Unknown authors · PubMed 33762635

  ABSTRACT: The combination of substance use and psychiatric disorders is one of the most common comorbidities. The objective of this study was to perform a genome-wide association study of this comorbidity (Com), substance use alone (Subs), and psychiatric symptomatology alone (Psych) in the Mexican population. The study included 3914 individuals of Mexican descent. Genotyping was carried out using the PsychArray microarray and genome-wide correlations were calculated. Genome-wide associations were analyzed using multiple logistic models, polygenic risk scores (PRSs) were evaluated using multinomial models, and vertical pleiotropy was evaluated by generalized summary-data-based Mendelian randomization. Brain DNA methylation quantitative loci (brain meQTL) were also evaluated in the prefront

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