rs10764342 - PIP4K2A

Magnitude 2.0 · 1 study on file

Reported associations

• Cognitive processing speed and accuracy are intrinsically different in genetic architecture and brain phenotypes - Unknown journal (n.d.) · Unknown authors · PubMed 39242605

  ABSTRACT: Since the birth of cognitive science, researchers have used reaction time and accuracy to measure cognitive ability. Although recognition of these two measures is often based on empirical observations, the underlying consensus is that most cognitive behaviors may be along two fundamental dimensions: cognitive processing speed (CPS) and cognitive processing accuracy (CPA). In this study, we used genomic-wide association studies (GWAS) data from 14 cognitive traits to show the presence of those two factors and revealed the specific neurobiological basis underlying them. We identified that CPS and CPA had distinct brain phenotypes (e.g. white matter microstructure), neurobiological bases (e.g. postsynaptic membrane), and developmental periods (i.e. late infancy). Moreover, those two

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