rs10756423 - Y_RNA - PRDX1P1

Magnitude 2.8 · 1 study on file

Reported associations

• Genome‐wide association of individual vulnerability with alcohol‐associated liver disease: A Korean genome and epidemiology study - Unknown journal (n.d.) · Unknown authors · PubMed 34387878

  ABSTRACT: Abstract Background and aims The quantity of alcohol leading to alcohol‐associated liver disease (ALD) varies individually. Genetic backgrounds contributing to the divergence in individual susceptibility to alcohol‐induced liver damage have not been elucidated in detail. Approach and results Based on the Korean Genome and Epidemiology Study Health Examination (KoGES_HEXA) cohort data, 21,919 participants (40‐79 years old) were included and divided into cases and controls based on the ALD diagnostic criteria proposed by the American College of Gastroenterology. Data generated by a genome wide‐association study were analyzed using logistic regression to assess the risk of ALD development in nondrinkers, light drinkers, and heavy drinkers. We detected three loci, gamma‐glu

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