rs10746109 - ASCL4 - WSCD2

Magnitude 2.8 · 1 study on file

Reported associations

• Ethnicity- and sex-specific genome wide association study on Parkinson's disease - Unknown journal (n.d.) · Unknown authors · PubMed 37805635

  ABSTRACT: Most previous genome-wide association studies (GWASs) on Parkinson's disease (PD) focus on the European population. There are several sex-specific clinical differences in PD, but little is known about its genetic background. We aimed to perform an ethnicity-specific and sex-specific GWAS on PD in the Korean population. A total of 1050 PD patients and 5000 controls were included. For primary analysis, we performed a GWAS using a logistic additive model adjusted for age and sex. The same statistical models were applied to sex-specific analyses. Genotyping was performed using a customized microarray chip optimized for the Korean population. Nine single nucleotide polymorphisms (SNPs) including four in the SNCA locus and three from the PARK16 locus were associated with PD in Korean

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