rs10745340 - AP4B1, AP4B1-AS1

Magnitude 4.5 · 1 study on file

Reported associations

• Genome-wide association study identifies novel variants in olfactory, vitamin A, vitamin B, and cadherin pathways associated with learning and memory. - Scientific reports (2026) · Hopkins LN, Avgan N, Sutherland HG, Fernandez FE, Knowles EEM, Haupt LM, Blangero J, Glahn DC, Shum DHK, Lea RA, Griffiths LR · PubMed 41413636

  Learning and memory, as fundamental components of human cognition, are heritable traits that are highly variable between individuals and within populations. Investigation into the genetic basis of cognition is a prominent area of research, with genetic associations being previously reported for a wide range of cognitive phenotypes. Here we utilise a genome-wide association study (GWAS) approach to evaluate the contribution of genetic variation to learning and memory phenotypes in a comprehensively phenotyped, well-characterised, healthy, and unrelated cohort of individuals (n = 613). Cognitive phenotypes were assessed using nine comprehensive test batteries consisting of twenty-one cognitive performance assessments including IQ, five measures for visual and verbal learning, and fifteen

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