rs10647170 - PRMT3

Magnitude 2.2 · 1 study on file

Reported associations

  • Genome wide association studies of the Self-Rating of Effects of Ethanol (SRE) - Unknown journal (n.d.) · Unknown authors · PubMed 31270906

    ABSTRACT: The level of response (LR) to alcohol as measured with the Self-Report of the Effects of alcohol retrospective questionnaire (SRE) evaluates the number of standard drinks usually required for up to four effects. The need for a higher number of drinks for effects is genetically influenced and predicts higher risks for heavy drinking and alcohol problems. We conducted GWAS in the African-American (COGA-AA, N=1,527 from 309 families) and European-American (COGA-EA, N=4,723 from 956 families) subsamples of the Collaborative Studies on the Genetics of Alcoholism (COGA) for two SRE scores: SRE-T (average of first 5 times of drinking, the period of heaviest drinking, and the most recent three months of consumption) and SRE-5 (the first 5 time of drinking). We then meta-analyzed the two


Auto-generated from study metadata. AI-synthesised commentary is added when this entry is regenerated through content-service's LLM mode.

Lifestyle context

Concrete actions anchored to the cited research. We do not prescribe, we describe.

Lifestyle

  • alcohol consumption Moderate

    This variant is associated with reduced alcohol sensitivity, a genetic risk factor for alcohol dependence.

    Monitor your drinking patterns for signs of problematic use.