rs1061680 - LILRB1

Magnitude 2.2 · 1 study on file

Reported associations

• Polygenic Influences on the Behavioral Effects of Alcohol Withdrawal in a Mixed-Ancestry Population from the Collaborative Study on the Genetics of Alcoholism (COGA) - Unknown journal (n.d.) · Unknown authors · PubMed 37031923

  ABSTRACT: Alcohol Withdrawal (AW) is a feature of alcohol use disorder that may occur in up to half of individuals with chronic, heavy alcohol consumption whenever alcohol use is abruptly stopped or significantly reduced. To date, few genes have been robustly associated with AW; this may be partly due to most studies defining AW as a binary construct despite the multiple symptoms and their range in severity from mild to severe. The current study examined the effects of genome-wide loci on a factor score for AW in high risk and community family samples in the Collaborative Study for the Genetics of Alcoholism (COGA). In addition, we tested whether differentially expressed genes associated with alcohol withdrawal in model organisms are enriched in human genome-wide association study (GWAS) e

Auto-generated from study metadata. AI-synthesised commentary is added when this entry is regenerated through content-service's LLM mode.