rs1054636033 - SELENOK - CABYRP1

Magnitude 4.5 · 1 study on file

Reported associations

• Predicting Risks of Dry Eye Disease Development Using a Genome-Wide Polygenic Risk Score Model - Unknown journal (n.d.) · Unknown authors · PubMed 38767906

  ABSTRACT: Purpose The purpose of this study was to conduct a large-scale genome-wide association study (GWAS) and construct a polygenic risk score (PRS) for risk stratification in patients with dry eye disease (DED) using the Taiwan Biobank (TWB) databases. Methods This retrospective case-control study involved 40,112 subjects of Han Chinese ancestry, sourced from the publicly available TWB. Cases were patients with DED (n = 14,185), and controls were individuals without DED (n = 25,927). The patients with DED were further divided into 8072 young (<60 years old) and 6113 old participants (≥60 years old). Using PLINK (version 1.9) software, quality control was carried out, followed by logistic regression analysis with adjustments for sex, age, body mass index, depression, and manic episod

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