rs10507130 - UTP20

Magnitude 2.0 · 1 study on file

Reported associations

• Genome-wide association study for subclinical atherosclerosis in major arterial territories in the NHLBI's Framingham Heart Study - Unknown journal (n.d.) · Unknown authors · PubMed 17903303

  ABSTRACT: Introduction Subclinical atherosclerosis (SCA) measures in multiple arterial beds are heritable phenotypes that are associated with increased incidence of cardiovascular disease. We conducted a genome-wide association study (GWAS) for SCA measurements in the community-based Framingham Heart Study. Methods Over 100,000 single nucleotide polymorphisms (SNPs) were genotyped (Human 100K GeneChip, Affymetrix) in 1345 subjects from 310 families. We calculated sex-specific age-adjusted and multivariable-adjusted residuals in subjects tested for quantitative SCA phenotypes, including ankle-brachial index, coronary artery calcification and abdominal aortic calcification using multi-detector computed tomography, and carotid intimal medial thickness (IMT) using carotid ultrasonography. We e

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