rs10506701 - LINC02882

Magnitude 2.0 · 1 study on file

Reported associations

• Genome-wide association with bone mass and geometry in the Framingham Heart Study - Unknown journal (n.d.) · Unknown authors · PubMed 17903296

  ABSTRACT: Background Osteoporosis is characterized by low bone mass and compromised bone structure, heritable traits that contribute to fracture risk. There have been no genome-wide association and linkage studies for these traits using high-density genotyping platforms. Methods We used the Affymetrix 100K SNP GeneChip marker set in the Framingham Heart Study (FHS) to examine genetic associations with ten primary quantitative traits: bone mineral density (BMD), calcaneal ultrasound, and geometric indices of the hip. To test associations with multivariable-adjusted residual trait values, we used additive generalized estimating equation (GEE) and family-based association tests (FBAT) models within each sex as well as sexes combined. We evaluated 70,987 autosomal SNPs with genotypic call rate

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