rs10505648 - LINC02055

Magnitude 4.5 · 1 study on file

Reported associations

• Genome-wide association study identified new susceptibility loci for polycystic ovary syndrome. - Human reproduction (Oxford, England) (2015) · Lee H, Oh JY, Sung YA, Chung H, Kim HL, Kim GS, Cho YS, Kim JT · PubMed 25574032

  Are there any novel genetic markers of susceptibility to polycystic ovary syndrome (PCOS)? We identified a novel susceptibility locus on chromosome 8q24.2 and several moderately associated loci for PCOS in Korean women. PCOS is a highly complex disorder with significant contributions from both genetic and environmental factors. Previous genome-wide association studies (GWAS) in the Han Chinese population identified several risk loci for PCOS. However, GWAS studies on PCOS remain very few. The aim of this study was to identify novel markers of susceptibility to PCOS through GWAS. A two-stage GWAS was conducted. The initial discovery set for GWAS consisted of 976 PCOS cases and 946 controls. The second stage (replication study) included 249 PCOS cases and 778 controls. Patients were diagnose

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