rs10502699 - RPL12P40 - RN7SKP182

Magnitude 4.5 · 1 study on file

Reported associations

  • Genomewide Analyses of Psychological Resilience in US Army Soldiers - Unknown journal (n.d.) · Unknown authors · PubMed 31081985

    ABSTRACT: Though a growing body of preclinical and translational research is illuminating a biological basis for resilience to stress, little is known about the genetic basis of psychological resilience in humans. We conducted genomewide association studies (GWAS) of self-assessed (by questionnaire) and outcome-based (incident mental disorders from pre- to post-deployment) resilience among European (EUR) ancestry soldiers in the Army Study To Assess Risk and Resilience in Servicemembers (STARRS). Self-assessed resilience (N=11,492) was found to have significant common-variant heritability (h2=0.162, se=0.050, p=5.37×10−4), and to be significantly negatively genetically correlated with neuroticism (rg= −0.388, p=0.0092). GWAS results from the EUR soldiers revealed a genomewide signific


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