rs10499559 - CDCA7L - RAPGEF5

Magnitude 2.0 · 1 study on file

Reported associations

• A genome-wide association for kidney function and endocrine-related traits in the NHLBI's Framingham Heart Study - Unknown journal (n.d.) · Unknown authors · PubMed 17903292

  ABSTRACT: Background Glomerular filtration rate (GFR) and urinary albumin excretion (UAE) are markers of kidney function that are known to be heritable. Many endocrine conditions have strong familial components. We tested for association between the Affymetrix GeneChip Human Mapping 100K single nucleotide polymorphism (SNP) set and measures of kidney function and endocrine traits. Methods Genotype information on the Affymetrix GeneChip Human Mapping 100K SNP set was available on 1345 participants. Serum creatinine and cystatin-C (cysC; n = 981) were measured at the seventh examination cycle (1998-2001); GFR (n = 1010) was estimated via the Modification of Diet in Renal Disease (MDRD) equation; UAE was measured on spot urine samples during the sixth examination cycle (1995-1998) and was

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