rs10495397 - RYR2

Magnitude 4.5 · 1 study on file

Reported associations

  • Genomic Association Study for Cognitive Impairment in Parkinson's Disease - Unknown journal (n.d.) · Unknown authors · PubMed 33613413

    ABSTRACT: Background: Cognitive impairment is very common in Parkinson's disease (PD) and constitutes the most debilitating complication of this disease. However, to date, few studies have investigated a genome-wide association in the development of cognitive impairment of PD. We aimed to identify the genetic loci associated with cognitive impairment in patients with sporadic PD by ethnicity-specific genotyping. Materials and methods: We recruited 1,070 patients with PD and performed a genome-wide association study using the Korean Chip, a microarray chip containing 827,400 single-nucleotide polymorphisms (SNPs) optimized for the Korean population. Multiple logistic regression models adjusting for age, sex, years of education, and disease duration were used to compare between patients with


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