rs10494195 - CD101-AS1, CD101

Magnitude 4.5 · 1 study on file

Reported associations

• Sex-dimorphic gene effects on survival outcomes in people with coronary artery disease - Unknown journal (n.d.) · Unknown authors · PubMed 35959094

  ABSTRACT: Background Ischemic coronary heart disease (IHD) is the leading cause of death worldwide. Genetic variation is presumed to be a major factor underlying sex differences for IHD events, including mortality. The purpose of this study was to identify sex-specific candidate genes associated with all-cause mortality among people diagnosed with coronary artery disease (CAD). Methods We performed a sex-stratified, exploratory genome-wide association (GWAS) screen using existing data from CAD-diagnosed males (n = 510) and females (n = 174) who reported European ancestry from the Duke Catheterization Genetics biorepository. Extant genotype data for 785,945 autosomal SNPs generated with the Human Omni1-Quad BeadChip (Illumina, CA, USA) were analyzed using an additive inheritance model.

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