rs10492604 - LINC00374 - RNY4P29

Magnitude 2.0 · 1 study on file

Reported associations

• Genome-wide association of sleep and circadian phenotypes - BMC medical genetics (2007) · Gottlieb DJ, O'Connor GT, Wilk JB · PubMed 17903308

  ABSTRACT: Background Numerous studies suggest genetic influences on sleepiness and circadian rhythms. The Sleep Heart Health Study collected questionnaire data on sleep habits and sleepiness from 2848 Framingham Heart Study Offspring Cohort participants. More than 700 participants were genotyped using the Affymetrix 100K SNP GeneChip, providing a unique opportunity to assess genetic linkage and association of these traits. Methods Sleepiness (defined as the Epworth Sleepiness Scale score), usual bedtime and usual sleep duration were assessed by self-completion questionnaire. Standardized residual measures adjusted for age, sex and BMI were analyzed. Multipoint variance components linkage analysis was performed. Association of SNPs to sleep phenotypes was analyzed with both population-based

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