rs10489167 - NFYC

Magnitude 2.2 · 1 study on file

Reported associations

• Genetics of long-term treatment outcome in bipolar disorder. - Progress in neuro-psychopharmacology & biological psychiatry (2016) · Fabbri C, Serretti A · PubMed 26297903

  Bipolar disorder (BD) shows one of the strongest genetic predispositions among psychiatric disorders and the identification of reliable genetic predictors of treatment response could significantly improve the prognosis of the disease. The present study investigated genetic predictors of long-term treatment-outcome in 723 patients with BD type I from the STEP-BD (Systematic Treatment Enhancement Program for Bipolar Disorder) genome-wide dataset. BD I patients with >6months of follow-up and without any treatment restriction (reflecting a natural setting scenario) were included. Phenotypes were the total and depressive episode rates and the occurrence of one or more (hypo)manic/mixed episodes during follow-up. Quality control of genome-wide data was performed according to standard criteria an

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