rs10459299 - DOCK9-DT - RPS6P23

Magnitude 2.0 · 1 study on file

Reported associations

• Heritability and genome-wide association analyses of fasting plasma glucose in Chinese adult twins - Unknown journal (n.d.) · Unknown authors · PubMed 32682390

  ABSTRACT: Background Currently, diabetes has become one of the leading causes of death worldwide. Fasting plasma glucose (FPG) levels that are higher than optimal, even if below the diagnostic threshold of diabetes, can also lead to increased morbidity and mortality. Here we intend to study the magnitude of the genetic influence on FPG variation by conducting structural equation modelling analysis and to further identify specific genetic variants potentially related to FPG levels by performing a genome-wide association study (GWAS) in Chinese twins. Results The final sample included 382 twin pairs: 139 dizygotic (DZ) pairs and 243 monozygotic (MZ) pairs. The DZ twin correlation for the FPG level (rDZ = 0.20, 95% CI: 0.04-0.36) was much lower than half that of the MZ twin correlation

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