rs10440984 - NXPH1

Magnitude 2.2 · 1 study on file

Reported associations

• The first genome-wide association study of internet addiction; Revealed substantial shared risk factors with neurodevelopmental psychiatric disorders. - Research in developmental disabilities (2023) · Haghighatfard A, Ghaderi AH, Mostajabi P, Kashfi SS, Mohabati Somehsarayee H, Shahrani M, Mehrasa M, Haghighat S, Farhadi M, Momayez Sefat M, Shiryazdi AA, Ezzati N, Qazvini MG, Alizadenik A, Moghadam ER · PubMed 36566681

  Internet addiction disorder (IAD) is listed as a disorder requiring further studies in the diagnostic and statistical manual of mental disorders (DSM-V). Psychological studies showed significant co-morbidity of IAD with depression, alcohol abuse, and anxiety disorder. Etiology and genetic bases of IAD are unclear. Present study aimed to investigate the genetic, psychological, and cognitive bases of a tendency to internet addiction. DNA was extracted from blood samples of IADs (N = 16,520) and 18,000 matched non-psychiatric subjects. Genotyping for the subjects was performed using SNP Array. Psychological, neuropsychological, and neurological characteristics were conducted. Seventy-two SNPs in 24 genes have been detected significantly associated with IAD. Most of these SNPs were risk fact

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