rs10433859 - C1QTNF7-AS1

Magnitude 2.0 · 1 study on file

Reported associations

• Genome-wide association study of cognitive flexibility assessed by the Wisconsin Card Sorting Test - Unknown journal (n.d.) · Unknown authors · PubMed 30134085

  ABSTRACT: Cognitive flexibility is a critical component of executive function and is strongly influenced by genetic factors. We conducted a genome-wide association study of cognitive flexibility (as measured by perseverative errors on the Wisconsin Card Sorting Test) in two sets of African American (AA) and European American (EA) subjects (Yale-Penn-1: 1,411 AAs/949 EAs; Yale-Penn-2: 1,178 AAs/1,335 EAs). We examined the association of cognitive flexibility with genotyped or imputed SNPs across the genome. In AAs, two correlated common SNPs (rs7165213/rs35633795) in the downstream region of the noncoding gene LOC101927286 on chromosome 15 showed genome-wide significant (GWS) associations with cognitive flexibility (Yale-Penn-1: P = 6.0×10−9/1.3×10−8; Yale-Penn-2: P = 0.029/0.010; met

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