rs1043274 - CYB561D1

Magnitude 2.2 · 1 study on file

Reported associations

  • Novel Genetic Loci Identified for the Pathophysiology of Childhood Obesity in the Hispanic Population - Unknown journal (n.d.) · Unknown authors · PubMed 23251661

    ABSTRACT: Genetic variants responsible for susceptibility to obesity and its comorbidities among Hispanic children have not been identified. The VIVA LA FAMILIA Study was designed to genetically map childhood obesity and associated biological processes in the Hispanic population. A genome-wide association study (GWAS) entailed genotyping 1.1 million single nucleotide polymorphisms (SNPs) using the Illumina Infinium technology in 815 children. Measured genotype analysis was performed between genetic markers and obesity-related traits i.e., anthropometry, body composition, growth, metabolites, hormones, inflammation, diet, energy expenditure, substrate utilization and physical activity. Identified genome-wide significant loci: 1) corroborated genes implicated in other studies (MTNR1B, ZNF259


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Lifestyle context

Concrete actions anchored to the cited research. We do not prescribe, we describe.

Screening

  • weight and metabolic markers Moderate

    rs1043274 A allele associates with increased obesity-related trait risk in genome-wide association study

    annual weight, BMI, and metabolic panel assessment