rs10411643 - PLK5

Magnitude 2.8 · 1 study on file

Reported associations

• A large-scale genomic investigation of susceptibility to infection and its association with mental disorders in the Danish population - Unknown journal (n.d.) · Unknown authors · PubMed 31712607

  ABSTRACT: Infections and mental disorders are two of the major global disease burdens. While correlations between mental disorders and infections have been reported, the possible genetic links between them have not been assessed in large-scale studies. Moreover, the genetic basis of susceptibility to infection is largely unknown, as large-scale genome-wide association studies of susceptibility to infection have been lacking. We utilized a large Danish population-based sample (N = 65,534) linked to nationwide population-based registers to investigate the genetic architecture of susceptibility to infection (heritability estimation, polygenic risk analysis, and a genome-wide association study (GWAS)) and examined its association with mental disorders (comorbidity analysis and genetic corr

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