rs10274553 - CCDC71L - LINC02577

Magnitude 2.2 · 1 study on file

Reported associations

• GWAS and PheWAS of red blood cell components in a Northern Nevadan cohort - Unknown journal (n.d.) · Unknown authors · PubMed 31194788

  ABSTRACT: In this study, we perform a full genome-wide association study (GWAS) to identify statistically significantly associated single nucleotide polymorphisms (SNPs) with three red blood cell (RBC) components and follow it with two independent PheWASs to examine associations between phenotypic data (case-control status of diagnoses or disease), significant SNPs, and RBC component levels. We first identified associations between the three RBC components: mean platelet volume (MPV), mean corpuscular volume (MCV), and platelet counts (PC), and the genotypes of approximately 500,000 SNPs on the Illumina Infimum DNA Human OmniExpress-24 BeadChip using a single cohort of 4,673 Northern Nevadans. Twenty-one SNPs in five major genomic regions were found to be statistically significantly associ

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