rs10244704 - ZP3P2 - PSMC1P3

Magnitude 2.2 · 1 study on file

Reported associations

• Genome-wide association study of neck circumference identifies sex-specific loci independent of generalized adiposity - Unknown journal (n.d.) · Unknown authors · PubMed 33907307

  ABSTRACT: Background/objectives Neck circumference, an index of upper airway fat, has been suggested to be an important measure of body-fat distribution with unique associations with health outcomes such as obstructive sleep apnea and metabolic disease. This study aims to study the genetic bases of neck circumference. Methods We conducted a multi-ethnic genome-wide association study of neck circumference, adjusted and unadjusted for BMI, in up to 15,090 European Ancestry (EA) and African American (AA) individuals. Because sexually dimorphic associations have been observed for anthropometric traits, we conducted both sex-combined and sex-specific analysis. Results We identified rs227724 near the Noggin (NOG) gene as a possible quantitative locus for neck circumference in men (N = 8831,

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