rs10219495 - LINC02397 - MTCH2P2

Magnitude 2.2 · 1 study on file

Reported associations

• GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease - Unknown journal (n.d.) · Unknown authors · PubMed 21658281

  ABSTRACT: Background Epidemiologic evidence suggests a heritable component to risk for sudden cardiac arrest independent of risk for myocardial infarction. Recent candidate gene association studies for community sudden cardiac arrests have focused on a limited number of biological pathways and yielded conflicting results. We sought to identify novel gene associations for sudden cardiac arrest in patients with coronary artery disease by performing a genome-wide association study. Methods Tagging SNPs (n = 338,328) spanning the genome were typed in a case-control study comparing 89 patients with coronary artery disease and sudden cardiac arrest due to ventricular tachycardia or ventricular fibrillation to 520 healthy controls. Results Fourteen SNPs including 7 SNPs among 7 genes (ACYP2, AP1G

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