rs1019623 - RN7SKP279 - DNAJB6P1

Magnitude 4.5 · 1 study on file

Reported associations

• Investigating the Genetics of Hippocampal Volume in Older Adults without Dementia - Unknown journal (n.d.) · Unknown authors · PubMed 25625606

  ABSTRACT: Hippocampal atrophy is observed with ageing and age-related neurodegenerative disease. Identification of the genetic correlates of hippocampal volume (HV) and atrophy may assist in elucidating the mechanisms of ageing and age-related neurodegeneration. Using two community cohorts of older Caucasians we estimated the heritability of HV and examined associations of HV with previously identified single nucleotide polymorphisms (SNPs). In addition we undertook genome-association studies (GWAS) examining HV and HV atrophy. Participants were community-dwelling non-demented older adults from the longitudinal Sydney Memory and Ageing Study (Sydney MAS) (N = 498) and the Older Australian Twins Study (OATS) (N = 351) aged 65 and over. HV was measured using T1-weighted magnetic resonance im

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