rs10146136 - ATL1

Magnitude 2.2 · 1 study on file

Reported associations

• Genomic loci and molecular genetic mechanisms for hidradenitis suppurativa - Unknown journal (n.d.) · Unknown authors · PubMed 40650879

  ABSTRACT: Abstract Background Hidradenitis suppurativa (HS) is a common, chronic and debilitating inflammatory disease that most commonly affects intertriginous skin. Despite its high heritability, the genetic underpinnings of HS remain poorly understood. Objectives To identify genetic signals associated with HS, determine genetic relationships with other diseases and investigate potential molecular genetic mechanisms. Methods We performed a genome-wide association meta-analysis of six studies, totalling 4540 patients with HS and > 1 million control participants, and identified genetic correlations with other common diseases. We integrated the HS data with expression quantitative trait loci from 10 trait-relevant tissues, epigenomic and transcriptomic data from human scalp, differential ex

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