rs10144968 - RAD51B, RAD51B-AS1

Magnitude 2.8 · 1 study on file

Reported associations

• A variant within the FTO confers susceptibility to diabetic nephropathy in Japanese patients with type 2 diabetes - Unknown journal (n.d.) · Unknown authors · PubMed 30566433

  ABSTRACT: To explore novel genetic loci for diabetic nephropathy, we performed genome-wide association studies (GWAS) for diabetic nephropathy in Japanese patients with type 2 diabetes. We analyzed the association of 5,768,242 single nucleotide polymorphisms (SNPs) in Japanese patients with type 2 diabetes, 2,380 nephropathy cases and 5,234 controls. We further performed GWAS for diabetic nephropathy using independent Japanese patients with type 2 diabetes, 429 cases and 358 controls and the results of these two GWAS were combined with an inverse variance meta-analysis (stage-1), followed by a de novo genotyping for the candidate SNP loci (p < 1.0 × 10−4) in an independent case-control study (Stage-2; 1,213 cases and 1,298 controls). After integrating stage-1 and stage-2 data, we identi

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