rs10129899 - PPP1R13B-DT
Magnitude 2.2 · 1 study on file
Reported associations
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Novel risk loci for COVID-19 hospitalization among admixed American populations - Unknown journal (n.d.) · Unknown authors · PubMed 39361370
ABSTRACT: The genetic basis of severe COVID-19 has been thoroughly studied, and many genetic risk factors shared between populations have been identified. However, reduced sample sizes from non-European groups have limited the discovery of population-specific common risk loci. In this second study nested in the SCOURGE consortium, we conducted a genome-wide association study (GWAS) for COVID-19 hospitalization in admixed Americans, comprising a total of 4702 hospitalized cases recruited by SCOURGE and seven other participating studies in the COVID-19 Host Genetic Initiative. We identified four genome-wide significant associations, two of which constitute novel loci and were first discovered in Latin American populations (BAZ2B and DDIAS). A trans-ethnic meta-analysis revealed another novel
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Lifestyle context
Concrete actions anchored to the cited research. We do not prescribe, we describe.
Discuss with your doctor
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COVID-19 hospitalization risk and prevention Moderate
PPP1R13B-DT rs10129899 A allele associated with increased COVID-19 hospitalization risk in genome-wide association study (n=73,303).
Discuss personalized COVID-19 prevention strategies and vaccination status with healthcare provider.