rs10118507 - RN7SL159P - LINC00963

Magnitude 4.5 · 1 study on file

Reported associations

• Clinical and genetic factors associated with post-operative nausea and vomiting after propofol anaesthesia. - Acta anaesthesiologica Scandinavica (2023) · Ahlström SE, Bergman PH, Jokela RM, Olkkola KT, Kaunisto MA, Kalso EA · PubMed 37156489

  The incidence of post-operative nausea and vomiting (PONV) remains at about 30% despite all therapeutic efforts to reduce it. The clinical risk factors guiding the prophylactic treatment are well established, but genetic factors associated with PONV remain poorly known. The aim of this study was to explore clinical and genetic factors impacting PONV by performing a genome-wide association study (GWAS) together with relevant clinical factors as covariates, and systematically attempt to replicate previously reported PONV associations. Relevant clinical factors are explored with logistic regression model. This was an observational case control study in Helsinki University Hospital between 1 August 2006 and 31 December 2010. One thousand consenting women with elevated risk for PONV, undergoing

Auto-generated from study metadata. AI-synthesised commentary is added when this entry is regenerated through content-service's LLM mode.