rs10114707 - LINC03062

Magnitude 4.5 · 1 study on file

Reported associations

• Inflammatory Protein Profiles in Plasma of Candidaemia Patients and the Contribution of Host Genetics to Their Variability. - Frontiers in immunology (2021) · Matzaraki V, Le KTT, Jaeger M, Aguirre-Gamboa R, Johnson MD, Sanna S, Rosati D, Franke L, Zhernakova A, Fu J, Withoff S, Jonkers I, Li Y, Joosten LAB, Netea MG, Wijmenga C, Kumar V · PubMed 34512620

  Circulatory inflammatory proteins play a significant role in anti- host immune defence. However, little is known about the genetic variation that contributes to the variability of inflammatory responses in response to . To systematically characterize inflammatory responses in infection, we profiled 91 circulatory inflammatory proteins in peripheral blood mononuclear cells (PBMCs) stimulated with yeast isolated from 378 individuals of European origin from the 500 Functional Genomics (500FG) cohort of the Human Functional Genomics Project (HFGP) and Lifelines Deep cohort. To identify the genetic factors that determine variation in inflammatory protein responses, we correlated genome-wide single nucleotide polymorphism (SNP) genotypes with protein abundance (protein quantitative trait loci, p

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