rs10114508 - RN7SL100P - PLAA

Magnitude 2.0 · 1 study on file

Reported associations

• Genome-wide association study identifies candidate loci associated with chronic pain and postherpetic neuralgia - Unknown journal (n.d.) · Unknown authors · PubMed 33685280

  ABSTRACT: Background Human twin studies and other studies have indicated that chronic pain has heritability that ranges from 30% to 70%. We aimed to identify potential genetic variants that contribute to the susceptibility to chronic pain and efficacy of administered drugs. We conducted genome-wide association studies (GWASs) using whole-genome genotyping arrays with more than 700,000 markers in 191 chronic pain patients and a subgroup of 89 patients with postherpetic neuralgia (PHN) in addition to 282 healthy control subjects in several genetic models, followed by additional gene-based and gene-set analyses of the same phenotypes. We also performed a GWAS for the efficacy of drugs for the treatment of pain. Results Although none of the single-nucleotide polymorphisms (SNPs) were found to

Auto-generated from study metadata. AI-synthesised commentary is added when this entry is regenerated through content-service's LLM mode.