rs10093384 - CNBD1 - SOX5P1

Magnitude 2.8 · 1 study on file

Reported associations

• Genomewide Association Study of Acute Anterior Uveitis Identifies New Susceptibility Loci - Unknown journal (n.d.) · Unknown authors · PubMed 32492107

  ABSTRACT: Purpose Acute anterior uveitis (AAU) is a common intraocular inflammatory disease. AAU occurs in 30% to 50% of patients with ankylosing spondylitis (AS), and both conditions are strongly associated with human leukocyte antigen (HLA)-B27, implying a shared etiology. This study aims to apply genomewide association study (GWAS) to characterize the genetic associations of AAU and their relationship to the genetics of AS. Methods We undertook the GWAS analyses in 2752 patients with AS with AAU (cases) and 3836 patients with AS without AAU (controls). There were 7,436,415 single-nucleotide polymorphisms (SNPs) available after SNP microarray genotyping, imputation, and quality-control filtering. Results We identified one locus associated with AAU at genomewide significance: rs9378248 (P

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