rs10092241 - HNF4G - RNU2-54P

Magnitude 2.0 · 1 study on file

Reported associations

• Investigating the shared genetic architecture between adiposity measures and obesity-related cancers - Briefings in bioinformatics (2025) · Wang S, Liu H, Yang Y, Wang Q, Zhang C, Zhang S, Gong J, Zhong R · PubMed 40874817

  ABSTRACT: Abstract Fat distribution patterns are increasingly linked to obesity-related cancers; however, their shared genetic determinants remain unclear. To identify shared genetic architecture between adiposity measures and obesity-related cancers. Utilizing large-scale summary statistics from genome-wide association study, we conducted genome-wide cross trait analyses of nine adiposity measures [body mass index (BMI), waist-to-hip (WTH) ratio, waist-to-hip ratio adjusted for BMI, arm fat ratio, trunk fat ratio, leg fat ratio, abdominal subcutaneous adipose tissue, gluteofemoral adipose tissue, and visceral adipose tissue] in five obesity-related cancers (colorectal cancer, esophageal adenocarcinoma, breast cancer, endometrial cancer, and ovarian cancer) to characterize their shared gen

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