rs1007500 - MAST4

Magnitude 2.2 · 1 study on file

Reported associations

• A genome-wide association study of n-3 and n-6 plasma fatty acids in a Singaporean Chinese population. - Genes & nutrition (2015) · Dorajoo R, Sun Y, Han Y, Ke T, Burger A, Chang X, Low HQ, Guan W, Lemaitre RN, Khor CC, Yuan JM, Koh WP, Ong CN, Tai ES, Liu J, van Dam RM, Heng CK, Friedlander Y · PubMed 26584805

  Polyunsaturated fatty acids (PUFAs) have a major impact on human health. Recent genome-wide association studies (GWAS) have identified several genetic loci that are associated with plasma levels of n-3 and n-6 PUFAs in primarily subjects of European ancestry. However, the relevance of these findings has not been evaluated extensively in other ethnic groups. The primary aim of this study was to evaluate for genetic loci associated with n-3 and n-6 PUFAs and to validate the role of recently identified index loci using data from a Singaporean Chinese population. Using a GWAS approach, we evaluated associations with plasma concentrations of three n-3 PUFAs [alphalinolenic acid (ALA), eicosapentaenoic acid and docosahexaenoic acid], four n-6 PUFAs [linoleic acid (LA), gammalinolenic acid, dihom

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