rs1007175 - LINC00359

Magnitude 2.0 · 1 study on file

Reported associations

• Genetic Survey of Adult-Onset Idiopathic Intracranial Hypertension - Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society (2020) · Kuehn MH, Mishra R, Deonovic BE, Miller KN, McCormack SE, Liu GT, Kupersmith MJ, Wall M · PubMed 29608535

  ABSTRACT: Background: Idiopathic intracranial hypertension (IIH) is a condition characterized by increased intracranial pressure of unknown cause. IIH has been shown to be associated with female sex as well as obesity. This genome-wide association study was performed to determine whether genetic variants are associated with this condition. Methods: We analyzed the chromosomal DNA of 95 patients with IIH enrolled in the Idiopathic Intracranial Hypertension Treatment Trial and 95 controls matched on sex, body mass index, and self-reported ethnicity. The samples were genotyped using Illumina Infinium HumanCoreExome v1-0 array and analyzed using a generalized linear mixed model that accounted for population stratification using multidimensional scaling. Results: A total of 301,908 single nuc

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